RHD(S103P)

Structure

RHD(S103P)

Key changes from standard allele

307T>C (S103P)

ISBT allele designation

RHD*39

Nucleotide changes relative to "standard RHD"

c.307 T>C

Amino acid changes relative to standard protein

Ser to Pro at codon 103

S103P

Haplotype (typical)

cDE

Allele cluster

Eurasian D cluster

Descriptions

First full publication: 1996 Faas BH et. al. Transfusion. 1996 Jun;36(6):506-11.

Other relevant descriptions:
DIII-like FR748227 (submitted 2010-12-13, released 2011-12-13)

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

G negative Faas BH et. al. Transfusion. 1996 Jun;36(6):506-11.

Observations

No data

Related Alleles

DHAR [RHCE-RHD(5)-RHCE]
DIII type 7 [RHD-RHCE(2)-RHD(A137V,N152T,T201R,F223V)]
DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D [DIIIa-ceS(1-2)-D(3)-ceS(4-7)-D]
DIIIb (Caucasian) [RHD-RHCE(2)-RHD]
RHD-ceAG.05(2)-D [RHD-RHCE(2)-RHD(A85G)]
DKK [RHD-RHCE(2-3)-RHD]
DIII type 4.2 [RHD(L62F,S103P,A137V,N152T)]
DIV(S103P) [RHD(L62F,S103P,A137V,N152T)]
DVII type 2 [RHD(S103P,L110P)]
RHD(I60V,S103P,F161S,L214F) [RHD(I60V,S103P,F161S,L214F)]
RHCE(1-3)-RHD(4-10) [RHD(Hybrid RHCE(1-3))]
RHCE(1-9)-RHD [RHCE(1-9)-RHD]
RHD-RHCE(2-10) [RHD-RHCE(2-10)]
RHD-RHCE(2-5)-RHD [RHD-RHCE(2-5)-RHD]

Additional comments

This allele is grouped as partial D, because it is G negative and grouping with "normal D" seemed inappropriate

Last update: 2017-01-29 (yyyy-MM-dd)