RHD-RHCE(2-5)-RHD

Structure

RHD-RHCE(2-5)-RHD

Key changes from standard allele

Hybrid RHCE(2-5)

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.[150 T>C;178 A>C;201 G>A;203 G>A;307 T>C;361 T>A;380 T>C;383 A>G;455 A>C;505 A>C;509 T>G;514 A>T;544 T>A;577 G>A;594 A>T;602 C>G;667 T>G;697 G>C;712 G>A;733 G>C;744 C>T;787 G>A;800 A>T]

Amino acid changes relative to standard protein

, I60L, S68N, S103P, L121M, V127A, D128G, N152T, M169L, M170R, I172F, S182F, E193K, K198N, T201R, F223V, E233Q, V238M, V245L, G263R, K267M

Phenotypes observed

CcDee (major)

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

Other relevant descriptions:
Gu J et. al. BMC Med Genet. 2014 May 5;15:54

ISBT group

Phenotype characterization and grouping

DEL

Serology

DEL Gu J et. al. BMC Med Genet. 2014 May 5;15:54

Observations

China (general): 1 of 41 DEL probands (among 42306 probands) Gu J et. al. BMC Med Genet. 2014 May 5;15:54

Additional comments

Last update: 2018-02-18 (yyyy-MM-dd)