weak RHD(IVS4+5G>A)

Structure

RHD(IVS4+5G>A)

Key changes from standard allele

IVS4+5G>A

ISBT allele designation

No designation assigned

Nucleotide changes relative to "standard RHD"

c.634+5 G>A

Amino acid changes relative to standard protein

ISBT group

Phenotype characterization and grouping

weakened D expression

Phenotypes observed

cDEe (major)

Haplotype (typical)

CDe

Allele cluster

Eurasian D cluster

Descriptions

First submission to GenBank: 2009 EU604754 (submitted 2008-03-28, released 2009-12-01)

First full publication: 2013 Ye L et. al. Transfusion. 2013 Aug;53(8):1829-33. doi: 10.1111/trf.12002. Epub 2012 Dec 7.

Serology

weakened D expresssion Ye L et. al. Transfusion. 2013 Aug;53(8):1829-33. doi: 10.1111/trf.12002. Epub 2012 Dec 7.

Observations

China (general): EU604754

Additional comments

In the initial publication, the allele was dubbed weak D type 82. This nomenclature was not approved by ISBT.

Last update: 2018-05-23 (yyyy-MM-dd)