RHD(F175L)

Structure

RHD(F175L)

Key changes from standard allele

525C>A (F175L)

ISBT allele designation

RHD*59

Nucleotide changes relative to "standard RHD"

c.525 C>A

Amino acid changes relative to standard protein

Phe to Leu at codon 175

F175L

Haplotype (typical)

not reported

Allele cluster

Eurasian D cluster

Descriptions

ISBT group

partial RHD

Phenotype characterization and grouping

Partial D

Serology

No data

Observations

No data

Additional comments

This allele is listed by ISBT as RHD*59 with a c.525C>T mutation. c.525C>T is a silent mutation and does not fit the F175L substitution reported. I did not yet locate the source and the substitution may be either c.525C>A or c.525C>G.

Last update: 2018-02-17 (yyyy-MM-dd)